Plasma Atherogenic Index is an Independent Indicator of Subclinical Atherosclerosis in Systemic Lupus Erythematosus

Plasma Atherogenic Index is an Independent Indicator of Subclinical Atherosclerosis in Systemic Lupus Erythematosus.

Objective Systemic lupus erythematosus (SLE) is characterized by chronic inflammation. Plasma atherogenic index (PAI) is a valuable marker for the cardiovascular disease and cardiac risk. The aim of this study was to evaluate the role and clinical use of PAI in atherosclerosis and the cardiac risk in SLE patients. Materials and Methods We included 56 female SLE patients who were selected acco...

Subclinical atherosclerosis in rheumatoid arthritis and systemic lupus erythematosus.

Rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) are associated with increased mortality, largely as a consequence of cardiovascular disease. Increased cardiovascular morbidity and mortality in patients with RA and SLE cannot be entirely explained by traditional risk factors, suggesting that the systemic inflammation that characterizes these diseases may accelerate atheroscleros...

How to predict subclinical atherosclerosis in systemic lupus erythematosus.

Autoimmunity and atherosclerosis (ATS) are linked: ANA positivity is associated with decreased carotid elasticity in women [1]. Subclinical ATS is an asymptomatic but highly prevalent condition of vascular disease [2] and, in patients with SLE, may develop at an early age due to inflammatory and immune-mediated mechanisms, oxidative stress and endothelial dysfunction [3]. An early diagnosis of ...

Neurobrucellosis in systemic lupus erythematosus

Background: Brucellosis is a zoonotic infection which is endemic in many countries. It is a multisystem disease which may present with a broad spectrum of clinical manifestations and complications. Neurobrucellosis is an uncommon complication of brucellosis. Case presentation: A 25-year-old woman with a history of lupus for 5 months referred to the emergency ward of Shahid Beheshti Hosp...

Studies of Atherosclerosis in Systemic Lupus Erythematosus